Demyelination, oedema and gliosis extend MRI T2 relaxation time. Hyperintensities in Fluid-attenuated inversion recovery (FLAIR) images indicate MS lesion presence. Automated algorithms segment lesions reproducibly, reducing inter-rater bias. In large projects such as clinical trials, hundreds of datasets can be processed simultaneously using parallel computing, saving time and money.
References: Schmidt, P., Gaser, C., Arsic, M., Buck, D., Förschler, A., Berthele, A., … & Hemmer, B. (2012). An automated tool for detection of FLAIR-hyperintense white-matter lesions in multiple sclerosis. Neuroimage, 59(4), 3774-3783.
Tools: Lesion segmentation Tool
FDA cleared: Research use
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